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sentix Investmentmeinung 31-2018

To do this, T-cells make contact with the antigen-presenting immune cells and read information from their surface. Both cells form a ring-shaped structure made of different proteins at the point of contact between the cells — termed immunological synapse — over which they can exchange information. At the end of this process the T-cell is either activated or remains inactive.

The T-cell makes contact with the antigen-presenting cell by means of specialized adhesion molecules which initially are randomly distributed over the cell surface. The loose bond formed between the two cell surfaces allows for the binding of T-cell receptors to the presented antigen. Where immunological synapses are correctly formed, the receptor molecules are concentrated around a central point whereas the other surface proteins arrange themselves into two rings around this central area.

Microscope image shows an immunological synapse.

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This, however, could not be proved for the other molecules. Dustin to simulate the formation of synapses using computer models. In these models, they simulated different conditions and influencing factors and were able to demonstrate that the different molecules exert an influence on each other in terms of their arrangement although they do not interact directly.

Computer simulation of an immunological synapse with its characteristic ring-shaped structure. The antigen receptors are small and are repelled by the large adhesion molecules.

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Power fluctuations in wind turbines push electricity grids to their limits Copyright: This leaves more time to analyse the calculation results in further dimensions and to obtain new findings. Besides, some calculations have only become possible with the introduction of the new system, which is why we consider the cooperation with the JSC to be extraordinarily successful," explains Stefan Schuh, who is responsible for the cooperation on the part of TenneT.


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The grid operator uses extensive simulation tools to plan the construction and dimensioning of new power lines. Due to grid bottlenecks, the output power of power plants, wind turbines and photovoltaic systems must on occasion be temporarily limited in order to stabilise grid operation.

However, curtailing of renewable energies only takes place in an emergency, as a last measure, in case of permanent overload.

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